ExoticRx · exoticrx.com/drugs/rivaroxaban
US brand names:Xarelto
Rivaroxaban is dosed at 1–2 mg/kg PO q24h in dogs, per Swann JW, Garden OA, Fellman CL, et al. ACVIM consensus statement on the treatment of immune-mediated hemolytic anemia in dogs. J Vet Intern Med. 2019;33(3):1141-1172. doi:10.1111/jvim.15463; Blais MC, Bianco D, Goggs R, et al. Consensus on the rational use of antithrombotics in veterinary critical care (CURATIVE): domain 3-defining antithrombotic protocols. J Vet Emerg Crit Care. 2019;29(1):60-74. doi:10.1111/vec.12795 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1150 (2026-08-01).. Verify against current literature before clinical use.
Direct, selective factor Xa inhibitor that blocks the conversion of prothrombin to thrombin, preventing fibrin clot formation.
Bleeding risk. No reliable reversal agent in veterinary practice. Monitor for occult bleeding. Limited canine pharmacokinetic data.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | q24h | Weak | Swann JW, Garden OA, Fellman CL, et al. ACVIM consensus statement on the treatment of immune-mediated hemolytic anemia in dogs. J Vet Intern Med. 2019;33(3):1141-1172. doi:10.1111/jvim.15463; Blais MC, Bianco D, Goggs R, et al. Consensus on the rational use of antithrombotics in veterinary critical care (CURATIVE): domain 3-defining antithrombotic protocols. J Vet Emerg Crit Care. 2019;29(1):60-74. doi:10.1111/vec.12795 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1150 (2026-08-01). |
| Cat (Domestic) | PO | 1–2 mg/kg | q24h | Extrapolated |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.