Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Clindamycin is dosed at 5.5–11 mg/kg PO q12h in dogs, per ANTIROBE - Clindamycin Hydrochloride Capsules and Oral Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2017. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a2224602-6f04-4b83-968a-8c193230998f — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.311 (2026-08-01).. Clindamycin is used in dogs for Dental infections, osteomyelitis, skin, Toxoplasmosis. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Clindamycin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Antirobe, Cleocin
Contraindicated in Rabbit, Chinchilla, Hamster, Degu, Guinea Pig
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 5.5–11 mg/kg | q12h | 14-28 days for bone infections | Dental infections, osteomyelitis, skin | Strong | ANTIROBE - Clindamycin Hydrochloride Capsules and Oral Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2017. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a2224602-6f04-4b83-968a-8c193230998f — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.311 (2026-08-01). |
| PO | 12.5–25 mg/kg | q12h | 14-21 days | Toxoplasmosis | Moderate | ANTIROBE - Clindamycin Hydrochloride Capsules and Oral Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2017. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a2224602-6f04-4b83-968a-8c193230998f — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.311 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis. Bacteriostatic; bactericidal at high concentrations.
CONTRAINDICATED in rabbits, guinea pigs, hamsters, and chinchillas (fatal dysbiosis). Good bone penetration. May cause GI upset, esophagitis in cats.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Clindamycin dose ranges in dogs, with cited source references: PO 5.5–11 mg/kg q12h; PO 12.5–25 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Clindamycin in dogs: PO.
Cited course lengths for Clindamycin in dogs include: 14-28 days for bone infections; 14-21 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Clindamycin is indicated in dogs for: Dental infections, osteomyelitis, skin, Toxoplasmosis.
These are general warnings for Clindamycin across species; consult the dog dosing table above for species-specific guidance. CONTRAINDICATED in rabbits, guinea pigs, hamsters, and chinchillas (fatal dysbiosis). Good bone penetration. May cause GI upset, esophagitis in cats.
Why a species-specific page? Clindamycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.