Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dantrolene is used in dog for Malignant hyperthermia (emergency), Urethral sphincter spasm. Routes documented in dog: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Dantrolene in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Dantrium
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits calcium release from the sarcoplasmic reticulum via ryanodine receptor blockade, reducing skeletal muscle contraction strength.
Treatment of choice for malignant hyperthermia. Hepatotoxicity with chronic oral use. Muscle weakness. IV form requires large volume reconstitution. Monitor liver function.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Dantrolene pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.