Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Felbamate is dosed at 15–30 mg/kg PO q8h in dogs, per Ruehlmann D, Podell M, March P. Treatment of partial seizures and seizure-like activity with felbamate in six dogs. J Small Anim Pract. 2001;42(8):403-408. doi:10.1111/j.1748-5827.2001.tb02490.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.531 (2026-08-01). — Plumb's 10th ed (held) printed p.503, Felbamate monograph spanning p.503-504; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Felbamate is used in dogs for Refractory epilepsy. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Felbamate in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Felbatol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 15–30 mg/kg | q8h | Chronic use; monitor CBC and liver enzymes monthly | Refractory epilepsy | Weak | Ruehlmann D, Podell M, March P. Treatment of partial seizures and seizure-like activity with felbamate in six dogs. J Small Anim Pract. 2001;42(8):403-408. doi:10.1111/j.1748-5827.2001.tb02490.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.531 (2026-08-01). — Plumb's 10th ed (held) printed p.503, Felbamate monograph spanning p.503-504; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/animal) | Route | Source | As printed |
|---|---|---|---|
| 200 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.342 | • Small dogs: 200 mg/dog q8h PO, and increase to a maximum dose of 600 mg/ |
| 400 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.342 | • Large dogs: 400 mg/dog q8h. Increase dose gradually by 200-mg (15-mg/kg) in- |
| 1200 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.342 | crements until seizure control. Maximum dose for large dogs is 1200 mg/dog q8h. |
| Dose (mg/kg) | Route | Source | As printed |
|---|
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Dual mechanism: blocks NMDA receptor glycine recognition site and enhances GABA-A receptor function. Also blocks voltage-dependent sodium channels.
Risk of aplastic anemia and hepatotoxicity in humans — monitor CBC and liver enzymes. Veterinary use for refractory epilepsy. Drug interactions with phenobarbital and other AEDs.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Felbamate dose range in dogs, with cited source references: PO 15–30 mg/kg q8h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Felbamate in dogs: PO.
Cited course lengths for Felbamate in dogs include: Chronic use; monitor CBC and liver enzymes monthly. Duration depends on the indication — match it to the specific dose rule in the table above.
Felbamate is indicated in dogs for: Refractory epilepsy.
These are general warnings for Felbamate across species; consult the dog dosing table above for species-specific guidance. Risk of aplastic anemia and hepatotoxicity in humans — monitor CBC and liver enzymes. Veterinary use for refractory epilepsy. Drug interactions with phenobarbital and other AEDs.
Why a species-specific page? Felbamate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 15–20 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.342 | • Start with 15-20 mg/kg q8h PO, and increase as needed to control seizures. |
| 70 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.342 | Maximum dose is approximately 70 mg/kg q8h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.