Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Imepitoin is dosed at 10–30 mg/kg PO q12h in dogs, per Pexion -- EMA Summary of Product Characteristics. Germany: Boehringer Ingelheim Vetmedica GmbH; 2017.; Pexion 100 Mg Tablets for Dogs, Pexion 400 Mg Tablets for Dogs [UK Datasheet]. Boehringer Ingelheim Animal Health UK Ltd; 2014. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.665 (2026-08-01). — Plumb's 10th ed (held) printed p.637, Imepitoin monograph spanning p.637-638; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Imepitoin is used in dogs for Idiopathic epilepsy. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Imepitoin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Pexion
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–30 mg/kg | q12h | Long-term | Idiopathic epilepsy | Moderate | Pexion -- EMA Summary of Product Characteristics. Germany: Boehringer Ingelheim Vetmedica GmbH; 2017.; Pexion 100 Mg Tablets for Dogs, Pexion 400 Mg Tablets for Dogs [UK Datasheet]. Boehringer Ingelheim Animal Health UK Ltd; 2014. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.665 (2026-08-01). — Plumb's 10th ed (held) printed p.637, Imepitoin monograph spanning p.637-638; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10–30 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.217 | 10-30 mg/kg p.o. q12h. Doses towards the higher end of the range appear to be more effective. For the |
| 10 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.217 | e effective. For the control of anxiety, an initial dose of 10 mg/kg p.o. q12h is recommended, but the dose may be titrated up to 30 mg/kg p.o. q12h or down |
| 30 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.217 | o. q12h is recommended, but the dose may be titrated up to 30 mg/kg p.o. q12h or down to 5 mg/kg p.o. q12h as necessary, dependent on initial response. 202 |
| 5 | PO |
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Low-affinity partial agonist at benzodiazepine binding site of GABA-A receptor. Anticonvulsant without full benzodiazepine sedation.
Approved in EU/some markets for canine epilepsy. Not DEA-scheduled (advantage over phenobarbital). Less sedation. May be less effective than phenobarbital for severe epilepsy.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Imepitoin dose range in dogs, with cited source references: PO 10–30 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Imepitoin in dogs: PO.
Cited course lengths for Imepitoin in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Imepitoin is indicated in dogs for: Idiopathic epilepsy.
These are general warnings for Imepitoin across species; consult the dog dosing table above for species-specific guidance. Approved in EU/some markets for canine epilepsy. Not DEA-scheduled (advantage over phenobarbital). Less sedation. May be less effective than phenobarbital for severe epilepsy.
Why a species-specific page? Imepitoin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| e dose may be titrated up to 30 mg/kg p.o. q12h or down to 5 mg/kg p.o. q12h as necessary, dependent on initial response. 202 BSAVA Small Animal Formula |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.