Lamotrigine for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Lamotrigine is used in dog for Refractory epilepsy. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Lamotrigine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Lamictal
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–5 mg/kg | q12h | Titrate slowly over 4-6 weeks; indefinite use | Refractory epilepsy | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Blocks voltage-sensitive sodium channels, stabilizing neuronal membranes and inhibiting glutamate release. Also modulates high-voltage-activated calcium channels.
Side effects & warnings
Risk of serious dermatologic reactions (Stevens-Johnson syndrome). Must titrate dose slowly. Very limited veterinary data. Monitor for skin rashes.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Neurological drugs with dog dosing
Lamotrigine dosing in other species
Why a species-specific page? Lamotrigine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.