Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Lamotrigine is dosed at 2–5 mg/kg PO q12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Lamotrigine is used in dogs for Refractory epilepsy. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Lamotrigine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lamictal
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–5 mg/kg | q12h | Titrate slowly over 4-6 weeks; indefinite use | Refractory epilepsy | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Blocks voltage-sensitive sodium channels, stabilizing neuronal membranes and inhibiting glutamate release. Also modulates high-voltage-activated calcium channels.
Risk of serious dermatologic reactions (Stevens-Johnson syndrome). Must titrate dose slowly. Very limited veterinary data. Monitor for skin rashes.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Lamotrigine dose range in dogs, with cited source references: PO 2–5 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Lamotrigine in dogs: PO.
Cited course lengths for Lamotrigine in dogs include: Titrate slowly over 4-6 weeks; indefinite use. Duration depends on the indication — match it to the specific dose rule in the table above.
Lamotrigine is indicated in dogs for: Refractory epilepsy.
These are general warnings for Lamotrigine across species; consult the dog dosing table above for species-specific guidance. Risk of serious dermatologic reactions (Stevens-Johnson syndrome). Must titrate dose slowly. Very limited veterinary data. Monitor for skin rashes.
Why a species-specific page? Lamotrigine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.