Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Lacosamide is dosed at 5–10 mg/kg IV IV bolus over 15 min, then transition to PO in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Lacosamide is used in dogs for Status epilepticus / acute seizure clusters, Epilepsy / adjunctive anticonvulsant. Routes documented in dogs: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Lacosamide in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Vimpat
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | IV bolus over 15 min, then transition to PO | Single dose or short-term IV | Status epilepticus / acute seizure clusters | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 5–10 mg/kg | q12h | Chronic use; can load IV for acute seizures | Epilepsy / adjunctive anticonvulsant | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Enhances slow inactivation of voltage-gated sodium channels, selectively stabilizing hyperexcitable neuronal membranes. Also binds CRMP-2 mediating neurite outgrowth.
May cause PR interval prolongation — monitor ECG. Dose-dependent dizziness and ataxia. Schedule V controlled substance. Limited veterinary pharmacokinetic data.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Lacosamide dose ranges in dogs, with cited source references: IV 5–10 mg/kg IV bolus over 15 min, then transition to PO; PO 5–10 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Lacosamide in dogs: IV, PO.
Cited course lengths for Lacosamide in dogs include: Single dose or short-term IV; Chronic use; can load IV for acute seizures. Duration depends on the indication — match it to the specific dose rule in the table above.
Lacosamide is indicated in dogs for: Status epilepticus / acute seizure clusters, Epilepsy / adjunctive anticonvulsant.
These are general warnings for Lacosamide across species; consult the dog dosing table above for species-specific guidance. May cause PR interval prolongation — monitor ECG. Dose-dependent dizziness and ataxia. Schedule V controlled substance. Limited veterinary pharmacokinetic data.
Why a species-specific page? Lacosamide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.