Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tepoxalin is dosed at 10–20 mg/kg PO q24h (loading), then 10 mg/kg q24h in dogs, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.791 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.791' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.763; verified by finding the drug named there. If you are holding the book, turn to p.763. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Tepoxalin is used in dogs for Osteoarthritis. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Tepoxalin in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zubrin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 10–20 mg/kg | q24h (loading), then 10 mg/kg q24h | Long-term | Osteoarthritis | Moderate | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.791 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.791' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.763; verified by finding the drug named there. If you are holding the book, turn to p.763. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.791 | • 10 mg/kg q24h PO. It is safe to start with 20 mg/kg initially and use a dose |
| 20 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.791 | • 10 mg/kg q24h PO. It is safe to start with 20 mg/kg initially and use a dose |
| 10–20 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.791 | of 10-20 mg/kg because of its wide safety margin. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Dual inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (LOX) pathways, blocking prostaglandin and leukotriene synthesis simultaneously.
Dogs only. Rapidly disintegrating tablet — place on tongue. GI adverse effects. Not with other NSAIDs. Monitor hepatic and renal function. Novel dual mechanism.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tepoxalin dose range in dogs, with cited source references: PO 10–20 mg/kg q24h (loading), then 10 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tepoxalin in dogs: PO.
Cited course lengths for Tepoxalin in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Tepoxalin is indicated in dogs for: Osteoarthritis.
These are general warnings for Tepoxalin across species; consult the dog dosing table above for species-specific guidance. Dogs only. Rapidly disintegrating tablet — place on tongue. GI adverse effects. Not with other NSAIDs. Monitor hepatic and renal function. Novel dual mechanism.
Why a species-specific page? Tepoxalin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.