ExoticRx · exoticrx.com/drugs/tepoxalin
US brand names:Zubrin
Tepoxalin is dosed at 10–20 mg/kg PO q24h (loading), then 10 mg/kg q24h in dogs, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.791 (2026-08-01).. Verify against current literature before clinical use.
Dual inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (LOX) pathways, blocking prostaglandin and leukotriene synthesis simultaneously.
Dogs only. Rapidly disintegrating tablet — place on tongue. GI adverse effects. Not with other NSAIDs. Monitor hepatic and renal function. Novel dual mechanism.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–20 mg/kg | q24h (loading), then 10 mg/kg q24h | Moderate | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.791 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.