Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Aglepristone is used in dog for Pregnancy termination/Closed pyometra. Routes documented in dog: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Aglepristone in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Alizin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 10 mg/kg | Days 1, 2, and 8 (or days 1 and 2 for mismating) | 3 injections (days 1, 2, 8) for pyometra; 2 injections (days 1, 2) for mismating | Pregnancy termination/Closed pyometra | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitive progesterone receptor antagonist with high affinity. Blocks progesterone action on the uterus, terminating pregnancy or treating pyometra.
Pain at injection site. Not available in the US. Used for pregnancy termination and closed pyometra in Europe. Monitor for uterine discharge.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Aglepristone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.