Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Proligestone is dosed at 10–33 mg/kg SC Single injection; repeat q5-6 months in dogs, per Siwak CT, Gruet P, Woehrle F et al. (2000) (monograph reference list carries only the propentofylline citation; the proligestone monograph itself lists no numbered reference) — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.360 (2026-08-01).. Proligestone is used in dogs for Estrus suppression/Prevention. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Proligestone in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Delvosteron, Covinan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 10–33 mg/kg | Single injection; repeat q5-6 months | Single depot injection; repeat every 5 months for continued suppression | Estrus suppression/Prevention | Moderate | Siwak CT, Gruet P, Woehrle F et al. (2000) (monograph reference list carries only the propentofylline citation; the proligestone monograph itself lists no numbered reference) — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.360 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
14-alpha,17-alpha-progesterone derivative that suppresses estrus by inhibiting gonadotropin release. Long-acting depot injection.
Not available in US. Risk of pyometra and mammary changes. Local reactions at injection site. Do not use in animals with reproductive disorders.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Proligestone dose range in dogs, with cited source references: SC 10–33 mg/kg Single injection; repeat q5-6 months. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Proligestone in dogs: SC.
Cited course lengths for Proligestone in dogs include: Single depot injection; repeat every 5 months for continued suppression. Duration depends on the indication — match it to the specific dose rule in the table above.
Proligestone is indicated in dogs for: Estrus suppression/Prevention.
These are general warnings for Proligestone across species; consult the dog dosing table above for species-specific guidance. Not available in US. Risk of pyometra and mammary changes. Local reactions at injection site. Do not use in animals with reproductive disorders.
Why a species-specific page? Proligestone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.