Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Proligestone is dosed at 10–33 mg/kg SC Single injection; repeat q5-6 months in dogs, per Siwak CT, Gruet P, Woehrle F et al. (2000) (monograph reference list carries only the propentofylline citation; the proligestone monograph itself lists no numbered reference) — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.360 (2026-08-01). — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705. Proligestone is used in dogs for Estrus suppression/Prevention. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Proligestone in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Delvosteron, Covinan
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 10–33 mg/kg | Single injection; repeat q5-6 months | Single depot injection; repeat every 5 months for continued suppression | Estrus suppression/Prevention |
| Siwak CT, Gruet P, Woehrle F et al. (2000) (monograph reference list carries only the propentofylline citation; the proligestone monograph itself lists no numbered reference) — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.360 (2026-08-01). — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10–33 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.360 | 10-33 mg/kg depending on body weight: Body weight (kg) Dose (mg) <5 |
| 10 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.360 | 550-600 thereafter 10 mg/kg This dose should be given once for the suppression of oestrus. If permanent postpo |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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14-alpha,17-alpha-progesterone derivative that suppresses estrus by inhibiting gonadotropin release. Long-acting depot injection.
Not available in US. Risk of pyometra and mammary changes. Local reactions at injection site. Do not use in animals with reproductive disorders.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Proligestone dose range in dogs, with cited source references: SC 10–33 mg/kg Single injection; repeat q5-6 months. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Proligestone in dogs: SC.
Cited course lengths for Proligestone in dogs include: Single depot injection; repeat every 5 months for continued suppression. Duration depends on the indication — match it to the specific dose rule in the table above.
Proligestone is indicated in dogs for: Estrus suppression/Prevention.
These are general warnings for Proligestone across species; consult the dog dosing table above for species-specific guidance. Not available in US. Risk of pyometra and mammary changes. Local reactions at injection site. Do not use in animals with reproductive disorders.
Why a species-specific page? Proligestone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.