ExoticRx · exoticrx.com/drugs/proligestone
US brand names:Delvosteron, Covinan
Proligestone is dosed at 10–33 mg/kg SC Single injection; repeat q5-6 months in dogs, per Siwak CT, Gruet P, Woehrle F et al. (2000) (monograph reference list carries only the propentofylline citation; the proligestone monograph itself lists no numbered reference) — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.360 (2026-08-01).. Verify against current literature before clinical use.
14-alpha,17-alpha-progesterone derivative that suppresses estrus by inhibiting gonadotropin release. Long-acting depot injection.
Not available in US. Risk of pyometra and mammary changes. Local reactions at injection site. Do not use in animals with reproductive disorders.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 10–33 mg/kg | Single injection; repeat q5-6 months | Moderate | Siwak CT, Gruet P, Woehrle F et al. (2000) (monograph reference list carries only the propentofylline citation; the proligestone monograph itself lists no numbered reference) — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.360 (2026-08-01). |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.