ExoticRx · exoticrx.com/drugs/estriol
US brand names:Incurin
Estriol is dosed at 0.5–2 mg/dog (PER ANIMAL - NOT mg/kg) PO q24h; 2 mg x14d min, then taper to 0.5 mg q24-48h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.483, Estriol monograph spanning p.483-484; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Estriol monograph, printed p.483-484; the earlier note claiming no held source contained this figure was wrong and has been removed. — figure located 2026-08-05 at Plumb's 10th ed printed p.484, Estriol monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
Short-acting natural estrogen that increases urethral sphincter tone and mucosal sensitivity. Minimal systemic estrogenic effects compared to other estrogens.
Lower risk of bone marrow suppression than other estrogens. Vulvar swelling and attracting males possible. Use lowest effective dose.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–2 mg/dog (PER ANIMAL - NOT mg/kg) | q24h; 2 mg x14d min, then taper to 0.5 mg q24-48h | Strong | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.483, Estriol monograph spanning p.483-484; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Estriol monograph, printed p.483-484; the earlier note claiming no held source contained this figure was wrong and has been removed. — figure located 2026-08-05 at Plumb's 10th ed printed p.484, Estriol monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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