ExoticRx · exoticrx.com/drugs/medroxyprogesterone-acetate
US brand names:Depo-Provera, Provera
Medroxyprogesterone Acetate is dosed at 2–5 mg/kg SC Single injection during anestrus in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Synthetic progestin that suppresses gonadotropin secretion, inhibiting ovulation and estrus. Also used for behavioral modification and dermatologic conditions.
Increased risk of pyometra, mammary neoplasia, diabetes mellitus, and adrenocortical suppression. Use spaying as preferred alternative. Not for long-term use.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.