Cat · Felis catus · typical adult weight 2.50–7.00 kg
Medroxyprogesterone Acetate is dosed at 2–5 mg/kg SC Single injection in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Medroxyprogesterone Acetate is used in cats for Estrus suppression/Behavioral (urine spraying). Routes documented in cats: SC. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Medroxyprogesterone Acetate in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Depo-Provera, Provera
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 2–5 mg/kg | Single injection | Single injection; effect lasts 2-6 months | Estrus suppression/Behavioral (urine spraying) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Synthetic progestin that suppresses gonadotropin secretion, inhibiting ovulation and estrus. Also used for behavioral modification and dermatologic conditions.
Increased risk of pyometra, mammary neoplasia, diabetes mellitus, and adrenocortical suppression. Use spaying as preferred alternative. Not for long-term use.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Medroxyprogesterone Acetate dose range in cats, with cited source references: SC 2–5 mg/kg Single injection. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Medroxyprogesterone Acetate in cats: SC.
Cited course lengths for Medroxyprogesterone Acetate in cats include: Single injection; effect lasts 2-6 months. Duration depends on the indication — match it to the specific dose rule in the table above.
Medroxyprogesterone Acetate is indicated in cats for: Estrus suppression/Behavioral (urine spraying).
These are general warnings for Medroxyprogesterone Acetate across species; consult the cat dosing table above for species-specific guidance. Increased risk of pyometra, mammary neoplasia, diabetes mellitus, and adrenocortical suppression. Use spaying as preferred alternative. Not for long-term use.
Why a species-specific page? Medroxyprogesterone Acetate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.