Cat · Felis catus · typical adult weight 2.50–7.00 kg
Aglepristone is dosed at 10–15 mg/kg SC Days 1 and 2 in cats, per Georgiev P, Wehrend A. Mid-gestation pregnancy termination by the progesterone antagonist aglepristone in queens. Theriogenology. 2006;65(7):1401-1406. / Fieni F, Martal J, Marnet PG, Siliart B, Guittot F. Clinical, biological and hormonal study of mid-pregnancy termination in cats with aglepristone. Theriogenology. 2006;66(6-7):1721-1728. doi:10.1016/j.theriogenology.2005.08.011 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.46 (2026-08-01).. Aglepristone is used in cats for Pregnancy termination/Pyometra. Routes documented in cats: SC. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Aglepristone in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Alizin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 10–15 mg/kg | Days 1 and 2 | 2 injections 24 hours apart; confirm by ultrasound at 7-10 days | Pregnancy termination/Pyometra |
| Georgiev P, Wehrend A. Mid-gestation pregnancy termination by the progesterone antagonist aglepristone in queens. Theriogenology. 2006;65(7):1401-1406. / Fieni F, Martal J, Marnet PG, Siliart B, Guittot F. Clinical, biological and hormonal study of mid-pregnancy termination in cats with aglepristone. Theriogenology. 2006;66(6-7):1721-1728. doi:10.1016/j.theriogenology.2005.08.011 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.46 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitive progesterone receptor antagonist with high affinity. Blocks progesterone action on the uterus, terminating pregnancy or treating pyometra.
Pain at injection site. Not available in the US. Used for pregnancy termination and closed pyometra in Europe. Monitor for uterine discharge.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Aglepristone dose range in cats, with cited source references: SC 10–15 mg/kg Days 1 and 2. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Aglepristone in cats: SC.
Cited course lengths for Aglepristone in cats include: 2 injections 24 hours apart; confirm by ultrasound at 7-10 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Aglepristone is indicated in cats for: Pregnancy termination/Pyometra.
These are general warnings for Aglepristone across species; consult the cat dosing table above for species-specific guidance. Pain at injection site. Not available in the US. Used for pregnancy termination and closed pyometra in Europe. Monitor for uterine discharge.
Why a species-specific page? Aglepristone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.