Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Aglepristone is dosed at 10 mg/kg IM, SC on day 1, 2, and 8 in guinea pigs, per Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.798 (2026-08-01, PENDING REVIEW). Aglepristone is used in guinea pigs for Pyometra/metritis (progesterone antagonist). Routes documented in guinea pigs: IM, SC. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Aglepristone in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Alizin
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM, SC | 10 mg/kg | on day 1, 2, and 8 | Pyometra/metritis (progesterone antagonist) | Moderate | Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.798 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitive progesterone receptor antagonist with high affinity. Blocks progesterone action on the uterus, terminating pregnancy or treating pyometra.
Pain at injection site. Not available in the US. Used for pregnancy termination and closed pyometra in Europe. Monitor for uterine discharge.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Aglepristone dose range in guinea pigs, with cited source references: IM, SC 10 mg/kg on day 1, 2, and 8. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Aglepristone in guinea pigs: IM, SC.
Aglepristone is indicated in guinea pigs for: Pyometra/metritis (progesterone antagonist).
These are general warnings for Aglepristone across species; consult the guinea pig dosing table above for species-specific guidance. Pain at injection site. Not available in the US. Used for pregnancy termination and closed pyometra in Europe. Monitor for uterine discharge.
Why a species-specific page? Aglepristone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.