Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Medroxyprogesterone Acetate is dosed at 2–5 mg/kg SC Single injection during anestrus in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Medroxyprogesterone Acetate is used in dogs for Estrus suppression. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Medroxyprogesterone Acetate in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Depo-Provera, Provera
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 2–5 mg/kg | Single injection during anestrus | Single injection; provides 4-6 months estrus suppression | Estrus suppression | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Synthetic progestin that suppresses gonadotropin secretion, inhibiting ovulation and estrus. Also used for behavioral modification and dermatologic conditions.
Increased risk of pyometra, mammary neoplasia, diabetes mellitus, and adrenocortical suppression. Use spaying as preferred alternative. Not for long-term use.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Medroxyprogesterone Acetate dose range in dogs, with cited source references: SC 2–5 mg/kg Single injection during anestrus. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Medroxyprogesterone Acetate in dogs: SC.
Cited course lengths for Medroxyprogesterone Acetate in dogs include: Single injection; provides 4-6 months estrus suppression. Duration depends on the indication — match it to the specific dose rule in the table above.
Medroxyprogesterone Acetate is indicated in dogs for: Estrus suppression.
These are general warnings for Medroxyprogesterone Acetate across species; consult the dog dosing table above for species-specific guidance. Increased risk of pyometra, mammary neoplasia, diabetes mellitus, and adrenocortical suppression. Use spaying as preferred alternative. Not for long-term use.
Why a species-specific page? Medroxyprogesterone Acetate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.