Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Mibolerone is used in dog for Estrus suppression. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Mibolerone in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Cheque Drops
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.03 mg/kg | q24h | Daily continuous; begin at least 30 days before expected estrus; max 24 months | Estrus suppression | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Synthetic androgen that suppresses estrus by inhibiting LH release from the anterior pituitary. Also has anabolic and progestational activity.
Hepatotoxic with prolonged use. Virilization of female animals. Do NOT use in cats (hepatotoxicity), Bedlington Terriers, or pregnant animals. Discontinued but still used.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Mibolerone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.