Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Estriol is used in dog for Urinary incontinence (spay incontinence). Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Estriol in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Incurin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.025–0.05 mg/kg | q24h for 14 days, then lowest effective dose | Loading dose 14 days, then taper to lowest effective maintenance dose (often every 2-3 days) | Urinary incontinence (spay incontinence) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Absolute dose ceiling, regardless of body weight: 2 mg total (PO).
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Short-acting natural estrogen that increases urethral sphincter tone and mucosal sensitivity. Minimal systemic estrogenic effects compared to other estrogens.
Lower risk of bone marrow suppression than other estrogens. Vulvar swelling and attracting males possible. Use lowest effective dose.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Estriol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.