Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Famotidine is used in dog for Acute GI ulceration, stress gastritis, Renal failure gastric protection, Stress gastritis prevention, Mast cell tumor gastric protection. Routes documented in dog: IV, PO, SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 6 cited dose rules for Famotidine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Pepcid
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.5–1 mg/kg | q12h | Until oral feasible | Acute GI ulceration, stress gastritis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| IV | 0.5–1 mg/kg | q12h | During hospitalization for AKI/CKD crisis | Renal failure gastric protection | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.5–1 mg/kg | q12h | During hospitalization | Stress gastritis prevention | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 1–2 mg/kg | q12h | During MCT treatment | Mast cell tumor gastric protection | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 0.5–1 mg/kg | q12-24h | 5-14 days or as needed | Gastric acid reduction, GI ulceration prevention | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| SC | 0.5–1 mg/kg | q12-24h | As needed | Gastric acid reduction | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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Competitively blocks histamine H2 receptors on parietal cells, reducing basal and stimulated gastric acid secretion.
Generally well-tolerated. Adjust dose in renal impairment. Less effective than proton pump inhibitors at acid suppression.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Famotidine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.