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Famotidine

Pepcid

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Routes

POIVSC

Indications

Acute gastritisAcute GI ulcerationGastric acid reductionGastric protectionGastric ulcerationGastric ulcers adjunctGI ulceration preventionHelicobacterMast cell tumor gastric protectionRenal failure gastric protectionstress gastritisStress gastritis prevention

Mechanism of Action

Competitively blocks histamine H2 receptors on parietal cells, reducing basal and stimulated gastric acid secretion.

Side effects & warnings

Generally well-tolerated. Adjust dose in renal impairment. Less effective than proton pump inhibitors at acid suppression.

Species with Famotidine dosing data (16 dose rules)

Species references:All African Grey Parrot drugsAll Bearded Dragon drugsAll Cat (Domestic) drugsAll Dog (Domestic) drugsAll Ferret drugsAll Guinea Pig drugsAll Horse (Equine) drugsAll Rabbit (Domestic) drugs

Evidence levels across 16 dose rules

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 3 published sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · ExoticRx 2026 (ferret dosing guide); Carpenter 6e
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 16 cited rules)

A dog/cat sample is shown here. Cited dosing for all 8 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)SC0.5–1 mg/kgq12-24hStrongPlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)IV0.5–1 mg/kgq12-24hStrongPlumb's Veterinary Drug Handbook, 9th Ed

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