Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Famotidine is dosed at 2.8 mg/kg PO q12h in horses, per Plumb's Veterinary Drug Handbook, 10th ed. (2023), printed p.500 (corpus plumb p.527), Famotidine, Dosages — HORSES. Underlying source: Duran SH, Ravis WR. Comparative pharmacokinetics of H2 antagonists in horses. Presented at: ACVIM Forum; 1993 (Plumb's ref 12).. Famotidine is used in horses for Gastric ulcers adjunct. Routes documented in horses: PO. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 1 cited dose rule for Famotidine in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Pepcid
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 2.8 mg/kg | q12h | Gastric ulcers adjunct | Weak | Plumb's Veterinary Drug Handbook, 10th ed. (2023), printed p.500 (corpus plumb p.527), Famotidine, Dosages — HORSES. Underlying source: Duran SH, Ravis WR. Comparative pharmacokinetics of H2 antagonists in horses. Presented at: ACVIM Forum; 1993 (Plumb's ref 12). |
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Competitively blocks histamine H2 receptors on parietal cells, reducing basal and stimulated gastric acid secretion.
Generally well-tolerated. Adjust dose in renal impairment. Less effective than proton pump inhibitors at acid suppression.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Famotidine dose range in horses, with cited source references: PO 2.8 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Famotidine in horses: PO.
Famotidine is indicated in horses for: Gastric ulcers adjunct.
These are general warnings for Famotidine across species; consult the horse dosing table above for species-specific guidance. Generally well-tolerated. Adjust dose in renal impairment. Less effective than proton pump inhibitors at acid suppression.
Why a species-specific page? Famotidine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.