Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Omeprazole (Equine Paste) is dosed at 1–2 mg/kg PO q24h in horses, per GASTROGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. / 25. ULCERGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d9a5b98-f039-4b45-8824-afd881c68998 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.982 (2026-08-01). — Plumb's 10th ed (held) printed p.955, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Omeprazole (Equine Paste) is used in horses for Gastric ulcers (EGUS) prevention, Gastric ulcers (EGUS) treatment. Routes documented in horses: PO. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Omeprazole (Equine Paste) in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: GastroGard, UlcerGard
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q24h | As needed during stress/training | Gastric ulcers (EGUS) prevention | Strong | GASTROGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. / 25. ULCERGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d9a5b98-f039-4b45-8824-afd881c68998 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.982 (2026-08-01). — Plumb's 10th ed (held) printed p.955, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 4 mg/kg | q24h | 28 days | Gastric ulcers (EGUS) treatment | Strong | GASTROGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d9a5b98-f039-4b45-8824-afd881c68998 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.982 (2026-08-01). — Plumb's 10th ed (held) printed p.955, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 4 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.608 | • Treating ulcers: 4 mg/kg once daily for 4 weeks PO. There is some evidence |
| 1–2 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.608 | that 1-2 mg/kg per day is as effective for treatment as a higher dose. Based on an |
| 1 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.608 | • Intravenous use (if a formulation is available): Loading dose of 1 mg/kg, followed |
| 1–2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.608 | • Preventing ulcers: 1-2 mg/kg q24h PO. (1 mg/kg was effective for prevention in |
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Irreversibly inhibits the H+/K+ ATPase proton pump in gastric parietal cells, suppressing basal and stimulated gastric acid secretion.
GastroGard (4mg/kg) for treatment of gastric ulcers; UlcerGard (1mg/kg) for prevention. Administer on empty stomach for optimal absorption. Not for use in horses intended for food.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Omeprazole (Equine Paste) dose ranges in horses, with cited source references: PO 1–2 mg/kg q24h; PO 4 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Omeprazole (Equine Paste) in horses: PO.
Cited course lengths for Omeprazole (Equine Paste) in horses include: As needed during stress/training; 28 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Omeprazole (Equine Paste) is indicated in horses for: Gastric ulcers (EGUS) prevention, Gastric ulcers (EGUS) treatment.
These are general warnings for Omeprazole (Equine Paste) across species; consult the horse dosing table above for species-specific guidance. GastroGard (4mg/kg) for treatment of gastric ulcers; UlcerGard (1mg/kg) for prevention. Administer on empty stomach for optimal absorption. Not for use in horses intended for food.
Why a species-specific page? Omeprazole (Equine Paste) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 1 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.608 | • Preventing ulcers: 1-2 mg/kg q24h PO. (1 mg/kg was effective for prevention in |
| 0.5 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.608 | by 0.5 mg/kg per day for 14-28 days. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.