Equine · Equus caballus · typical adult weight 350.00–700.00 kg
Omeprazole (Equine Paste) is dosed at 1–2 mg/kg PO q24h in horses, per GASTROGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. / 25. ULCERGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d9a5b98-f039-4b45-8824-afd881c68998 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.982 (2026-08-01).. Omeprazole (Equine Paste) is used in horses for Gastric ulcers (EGUS) prevention, Gastric ulcers (EGUS) treatment. Routes documented in horses: PO. A typical adult horse weighs 350.00–700.00 kg. ExoticRx lists 2 cited dose rules for Omeprazole (Equine Paste) in horses, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: GastroGard, UlcerGard
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q24h | As needed during stress/training | Gastric ulcers (EGUS) prevention | Strong | GASTROGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. / 25. ULCERGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d9a5b98-f039-4b45-8824-afd881c68998 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.982 (2026-08-01). |
| PO | 4 mg/kg | q24h | 28 days | Gastric ulcers (EGUS) treatment | Strong | GASTROGARD - Omeprazole Paste [US Product Label for Horses]. Boehringer Ingelheim Animal Health USA Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d9a5b98-f039-4b45-8824-afd881c68998 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.982 (2026-08-01). |
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Irreversibly inhibits the H+/K+ ATPase proton pump in gastric parietal cells, suppressing basal and stimulated gastric acid secretion.
GastroGard (4mg/kg) for treatment of gastric ulcers; UlcerGard (1mg/kg) for prevention. Administer on empty stomach for optimal absorption. Not for use in horses intended for food.
Species-specific contraindications and adverse-reaction reports for horses may differ from canine / feline reference data — consult the primary citations listed with each rule.
Omeprazole (Equine Paste) dose ranges in horses, with cited source references: PO 1–2 mg/kg q24h; PO 4 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Omeprazole (Equine Paste) in horses: PO.
Cited course lengths for Omeprazole (Equine Paste) in horses include: As needed during stress/training; 28 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Omeprazole (Equine Paste) is indicated in horses for: Gastric ulcers (EGUS) prevention, Gastric ulcers (EGUS) treatment.
These are general warnings for Omeprazole (Equine Paste) across species; consult the horse dosing table above for species-specific guidance. GastroGard (4mg/kg) for treatment of gastric ulcers; UlcerGard (1mg/kg) for prevention. Administer on empty stomach for optimal absorption. Not for use in horses intended for food.
Why a species-specific page? Omeprazole (Equine Paste) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in horses — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.