Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Mavacoxib is dosed at 2 mg/kg PO Day 0, Day 14, then monthly (max 7 doses) in dogs, per Cox SR, Lesman SP, Boucher JF et al. (2010) The pharmacokinetics of mavacoxib, a long-acting COX-2 inhibitor, in young adult laboratory dogs. Journal of Veterinary Pharmacology and Therapeutics 33, 461-470 | Cox SR, Liao S, Payne-Johnson M et al. (2011) Population pharmacokinetics of mavacoxib in osteoarthritic dogs. Journal of Veterinary Pharmaology and Therapeutics 34, 1-11 doi:10.1111/j.1365-2885.2010.01165.x — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.263 (2026-08-01).. Mavacoxib is used in dogs for Osteoarthritis (long-term). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Mavacoxib in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Trocoxil
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2 mg/kg | Day 0, Day 14, then monthly (max 7 doses) | Maximum 6.5 months continuous treatment | Osteoarthritis (long-term) | Strong | Cox SR, Lesman SP, Boucher JF et al. (2010) The pharmacokinetics of mavacoxib, a long-acting COX-2 inhibitor, in young adult laboratory dogs. Journal of Veterinary Pharmacology and Therapeutics 33, 461-470 | Cox SR, Liao S, Payne-Johnson M et al. (2011) Population pharmacokinetics of mavacoxib in osteoarthritic dogs. Journal of Veterinary Pharmaology and Therapeutics 34, 1-11 doi:10.1111/j.1365-2885.2010.01165.x — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.263 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective COX-2 inhibitor with extremely long half-life (44 days in dogs). Once-monthly dosing after initial loading.
Dogs only (EU-approved). Very long half-life — cannot rapidly discontinue if adverse effects. Not for dogs <12 months or <5kg. Monitor hepatic/renal. Maximum 7 doses (6.5 months).
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Mavacoxib dose range in dogs, with cited source references: PO 2 mg/kg Day 0, Day 14, then monthly (max 7 doses). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Mavacoxib in dogs: PO.
Cited course lengths for Mavacoxib in dogs include: Maximum 6.5 months continuous treatment. Duration depends on the indication — match it to the specific dose rule in the table above.
Mavacoxib is indicated in dogs for: Osteoarthritis (long-term).
These are general warnings for Mavacoxib across species; consult the dog dosing table above for species-specific guidance. Dogs only (EU-approved). Very long half-life — cannot rapidly discontinue if adverse effects. Not for dogs <12 months or <5kg. Monitor hepatic/renal. Maximum 7 doses (6.5 months).
Why a species-specific page? Mavacoxib pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.