ExoticRx · exoticrx.com/drugs/mavacoxib
US brand names:Trocoxil
Mavacoxib is dosed at 4 mg/kg PO single dose in cockatiels, per Dhondt L, Devreese M, Croubels S, De Baere S, Haesendonck R, Goessens T, Gehring R, De Backer P, Antonissen G. Comparative population pharmacokinetics and absolute oral bioavailability of COX-2 selective inhibitors celecoxib, mavacoxib and meloxicam in cockatiels (Nymphicus hollandicus). Sci Rep. 2017;7(1):12043. doi:10.1038/s41598-017-12159-z https://europepmc.org/article/PMC/PMC5612971. Verify against current literature before clinical use.
Selective COX-2 inhibitor with extremely long half-life (44 days in dogs). Once-monthly dosing after initial loading.
Dogs only (EU-approved). Very long half-life — cannot rapidly discontinue if adverse effects. Not for dogs <12 months or <5kg. Monitor hepatic/renal. Maximum 7 doses (6.5 months).
Species references:All Cat (Domestic) drugsAll Cockatiel drugsAll Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2 mg/kg | Day 0, Day 14, then monthly (max 7 doses) | Strong | Cox SR, Lesman SP, Boucher JF et al. (2010) The pharmacokinetics of mavacoxib, a long-acting COX-2 inhibitor, in young adult laboratory dogs. Journal of Veterinary Pharmacology and Therapeutics 33, 461-470 | Cox SR, Liao S, Payne-Johnson M et al. (2011) Population pharmacokinetics of mavacoxib in osteoarthritic dogs. Journal of Veterinary Pharmaology and Therapeutics 34, 1-11 doi:10.1111/j.1365-2885.2010.01165.x — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.263 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.263' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.247; verified by finding the drug named there. If you are holding the book, turn to p.247. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Veterinary Pharmacology and Therapeutics — ISBN 9781118855829, https://openlibrary.org/isbn/9781118855829 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.
| Cat (Domestic) | PO | See the cited source for the printed regimen | N/A | Extrapolated | Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.263 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.263' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.247; verified by finding the drug named there. If you are holding the book, turn to p.247. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705 |