ExoticRx · exoticrx.com/drugs/mavacoxib
Mavacoxib
Trocoxil
Drug Class
Routes
Indications
Mechanism of Action
Selective COX-2 inhibitor with extremely long half-life (44 days in dogs). Once-monthly dosing after initial loading.
Side effects & warnings
Dogs only (EU-approved). Very long half-life — cannot rapidly discontinue if adverse effects. Not for dogs <12 months or <5kg. Monitor hepatic/renal. Maximum 7 doses (6.5 months).
Species with Mavacoxib dosing data (2 dose rules)
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Evidence levels across 2 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by a published source
- · BSAVA Small Animal Formulary, 10th Ed
Sample dosing (2 of 2 cited rules)
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2 mg/kg | Day 0, Day 14, then monthly (max 7 doses) | Strong | BSAVA Small Animal Formulary, 10th Ed |
| Cat (Domestic) | PO | 0 N/A | N/A | Extrapolated | BSAVA Small Animal Formulary, 10th Ed |
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Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.