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Mavacoxib

Trocoxil

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

NSAID

Routes

PO

Indications

Not approvedOsteoarthritis (long-term)

Mechanism of Action

Selective COX-2 inhibitor with extremely long half-life (44 days in dogs). Once-monthly dosing after initial loading.

Side effects & warnings

Dogs only (EU-approved). Very long half-life — cannot rapidly discontinue if adverse effects. Not for dogs <12 months or <5kg. Monitor hepatic/renal. Maximum 7 doses (6.5 months).

Species with Mavacoxib dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Strong×1Extrapolated×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · BSAVA Small Animal Formulary, 10th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO2 mg/kgDay 0, Day 14, then monthly (max 7 doses)StrongBSAVA Small Animal Formulary, 10th Ed
Cat (Domestic)PO0 N/AN/AExtrapolatedBSAVA Small Animal Formulary, 10th Ed

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