Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Buspirone is dosed at 0.5–2 mg/kg PO q12h in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.184 (2026-08-01).. Buspirone is used in dogs for Generalized anxiety. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Buspirone in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: BuSpar
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q12h | Long-term | Generalized anxiety | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.184 (2026-08-01). |
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Partial agonist at serotonin 5-HT1A receptors. Anxiolytic without sedation, muscle relaxation, or anticonvulsant effects.
Takes 1-2 weeks for full effect. No sedation (unlike benzodiazepines). Not effective for acute anxiety/panic. Used for urine marking in cats, generalized anxiety in dogs. May increase aggression in some cats.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Buspirone dose range in dogs, with cited source references: PO 0.5–2 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Buspirone in dogs: PO.
Cited course lengths for Buspirone in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Buspirone is indicated in dogs for: Generalized anxiety.
These are general warnings for Buspirone across species; consult the dog dosing table above for species-specific guidance. Takes 1-2 weeks for full effect. No sedation (unlike benzodiazepines). Not effective for acute anxiety/panic. Used for urine marking in cats, generalized anxiety in dogs. May increase aggression in some cats.
Why a species-specific page? Buspirone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.