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Buspirone for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Buspirone is used in cat for Urine spraying/marking, fear-based aggression. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Buspirone in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: BuSpar

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO0.5–1 mg/kgq12hLong-termUrine spraying/marking, fear-based aggressionModeratePlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Partial agonist at serotonin 5-HT1A receptors. Anxiolytic without sedation, muscle relaxation, or anticonvulsant effects.

Side effects & warnings

Takes 1-2 weeks for full effect. No sedation (unlike benzodiazepines). Not effective for acute anxiety/panic. Used for urine marking in cats, generalized anxiety in dogs. May increase aggression in some cats.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Behavioral drugs with cat dosing

Buspirone dosing in other species

Why a species-specific page? Buspirone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.