Cat · Felis catus · typical adult weight 2.50–7.00 kg
Sertraline is dosed at 0.5–1.5 mg/kg PO q24h in cats, per Ogata N, Dantas LM de S, Crowell-Davis SL. Chapter 8: Selective Serotonin Reuptake Inhibitors. 2nd ed. (Crowell-Davis SL, Murray TF, Dantas LM de S, eds.). John Wiley & Sons, Inc.; 2019. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1182 (2026-08-01).. Sertraline is used in cats for Anxiety, compulsive behaviors. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Sertraline in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zoloft
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–1.5 mg/kg | q24h | Weeks to months | Anxiety, compulsive behaviors | Moderate | Ogata N, Dantas LM de S, Crowell-Davis SL. Chapter 8: Selective Serotonin Reuptake Inhibitors. 2nd ed. (Crowell-Davis SL, Murray TF, Dantas LM de S, eds.). John Wiley & Sons, Inc.; 2019. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1182 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective serotonin reuptake inhibitor with mild dopamine reuptake inhibition. Potent SSRI used for anxiety and compulsive disorders.
Used for separation anxiety, noise phobias, compulsive behaviors. 4-6 weeks for full effect. Serotonin syndrome risk. GI upset common initially. Do not use with MAO inhibitors.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Sertraline dose range in cats, with cited source references: PO 0.5–1.5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Sertraline in cats: PO.
Cited course lengths for Sertraline in cats include: Weeks to months. Duration depends on the indication — match it to the specific dose rule in the table above.
Sertraline is indicated in cats for: Anxiety, compulsive behaviors.
These are general warnings for Sertraline across species; consult the cat dosing table above for species-specific guidance. Used for separation anxiety, noise phobias, compulsive behaviors. 4-6 weeks for full effect. Serotonin syndrome risk. GI upset common initially. Do not use with MAO inhibitors.
Why a species-specific page? Sertraline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.