Cat · Felis catus · typical adult weight 2.50–7.00 kg
Olanzapine is dosed at 0.1–0.25 mg/kg PO q24h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Olanzapine is used in cats for Severe psychogenic alopecia refractory to SSRIs. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Olanzapine in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zyprexa
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–0.25 mg/kg | q24h | 6-8 week trial | Severe psychogenic alopecia refractory to SSRIs | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Antagonist at serotonin 5-HT2A/2C, dopamine D1-D4, muscarinic M1-M5, histamine H1, and alpha-1 adrenergic receptors. Broad receptor binding profile.
Weight gain and metabolic syndrome common. Sedation, especially at initiation. Risk of hepatotoxicity. Very limited veterinary data.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Olanzapine dose range in cats, with cited source references: PO 0.1–0.25 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Olanzapine in cats: PO.
Cited course lengths for Olanzapine in cats include: 6-8 week trial. Duration depends on the indication — match it to the specific dose rule in the table above.
Olanzapine is indicated in cats for: Severe psychogenic alopecia refractory to SSRIs.
These are general warnings for Olanzapine across species; consult the cat dosing table above for species-specific guidance. Weight gain and metabolic syndrome common. Sedation, especially at initiation. Risk of hepatotoxicity. Very limited veterinary data.
Why a species-specific page? Olanzapine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.