Alprazolam for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Alprazolam is used in dog for Noise phobia, panic anxiety. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Alprazolam in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Xanax
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.01–0.1 mg/kg | q4-12h as needed | Situational use | Noise phobia, panic anxiety | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Enhances GABA-A receptor activity by binding benzodiazepine site, increasing chloride conductance. Anxiolytic, sedative, and anticonvulsant.
Side effects & warnings
DEA Schedule IV. Paradoxical excitement possible in some animals. Hepatic metabolism. Dependence with chronic use — taper to discontinue. Cats: idiosyncratic hepatic necrosis (rare).
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Behavioral drugs with dog dosing
Alprazolam dosing in other species
Why a species-specific page? Alprazolam pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.