Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Pimobendan Injectable is dosed at 0.15 mg/kg IV Slow IV push 5min; then PO q12h in dogs, per Häggström J, Boswood A, O'Grady MR et al. (2008) Effect of pimobendan or benazepril hydrochloride on survival times in dogs with congestive heart failure caused by naturally occurring myxomatous mitral valve disease: the QUEST Study. Journal of Veterinary Internal Medicine 22, 1124-1135 doi:10.1111/j.1939-1676.2008.0150.x — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.343 (2026-08-01).. Pimobendan Injectable is used in dogs for Acute decompensated CHF, Cardiogenic shock (acute DMVD decompensation). Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Pimobendan Injectable in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Vetmedin Injection
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.15 mg/kg | Slow IV push 5min; then PO q12h | Single IV dose; transition to oral pimobendan as soon as patient can swallow | Acute decompensated CHF | Strong | Häggström J, Boswood A, O'Grady MR et al. (2008) Effect of pimobendan or benazepril hydrochloride on survival times in dogs with congestive heart failure caused by naturally occurring myxomatous mitral valve disease: the QUEST Study. Journal of Veterinary Internal Medicine 22, 1124-1135 doi:10.1111/j.1939-1676.2008.0150.x — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.343 (2026-08-01). |
| IV | 0.15–0.3 mg/kg | Slow IV push; may give second dose at 12h | 1-2 IV doses; oral formulation thereafter | Cardiogenic shock (acute DMVD decompensation) | Moderate | ACVIM DMVD Consensus; Vetmedin Injection Label |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Calcium sensitizer and phosphodiesterase III inhibitor providing positive inotropy without increasing oxygen demand, plus vasodilation reducing cardiac afterload.
For acute decompensated CHF when oral route not possible. Slow IV push over 5 minutes. Transition to oral pimobendan ASAP. Monitor heart rate and blood pressure.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Pimobendan Injectable dose ranges in dogs, with cited source references: IV 0.15 mg/kg Slow IV push 5min; then PO q12h; IV 0.15–0.3 mg/kg Slow IV push; may give second dose at 12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Pimobendan Injectable in dogs: IV.
Cited course lengths for Pimobendan Injectable in dogs include: Single IV dose; transition to oral pimobendan as soon as patient can swallow; 1-2 IV doses; oral formulation thereafter. Duration depends on the indication — match it to the specific dose rule in the table above.
Pimobendan Injectable is indicated in dogs for: Acute decompensated CHF, Cardiogenic shock (acute DMVD decompensation).
These are general warnings for Pimobendan Injectable across species; consult the dog dosing table above for species-specific guidance. For acute decompensated CHF when oral route not possible. Slow IV push over 5 minutes. Transition to oral pimobendan ASAP. Monitor heart rate and blood pressure.
Why a species-specific page? Pimobendan Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.