Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Doxycycline Hyclate Injectable is dosed at 5–10 mg/kg IV q12h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.436, Doxycycline monograph spanning p.433-437; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Doxycycline Hyclate Injectable is used in dogs for Severe infections (hospitalized). Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Doxycycline Hyclate Injectable in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Doxy Injectable
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | q12h | 7-14 days | Severe infections (hospitalized) | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.436, Doxycycline monograph spanning p.433-437; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.157 | 10 mg/kg p.o. q24h with food. |
| 5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.304 | • 5 mg/kg q12h PO or IV. 10 mg/kg q24h PO. |
| 10 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.304 | • Heartworm treatment (dogs): 10 mg/kg q12h, PO, administered for 28 days prior |
| 5 | — |
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Tetracycline binding 30S ribosomal subunit. IV formulation for patients unable to take oral medication.
IV administration must be slow (thrombophlebitis). Same spectrum as oral doxycycline. Not for IM/SC use. Monitor for GI upset.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Doxycycline Hyclate Injectable dose range in dogs, with cited source references: IV 5–10 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Doxycycline Hyclate Injectable in dogs: IV.
Cited course lengths for Doxycycline Hyclate Injectable in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Doxycycline Hyclate Injectable is indicated in dogs for: Severe infections (hospitalized).
These are general warnings for Doxycycline Hyclate Injectable across species; consult the dog dosing table above for species-specific guidance. IV administration must be slow (thrombophlebitis). Same spectrum as oral doxycycline. Not for IM/SC use. Monitor for GI upset.
Why a species-specific page? Doxycycline Hyclate Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| Papich Saunders Handbook of Veterinary Drugs, 4th edp.304 |
| • Ehrlichia (dogs): 5 mg/kg q12h for at least 14 days. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.