Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ondansetron Injectable is dosed at 0.1–0.5 mg/kg IV q8-12h IV in dogs, per Topal A, Kaya M, Gul N. Ondansetron and granisetron in the prophylaxis of nausea and emesis induced by cisplatin in dogs. Acta Vet Brno. 2005;74(1):111-116. / 1. Yalcin E, Keser GO. Comparative efficacy of metoclopramide, ondansetron and maropitant in preventing parvoviral enteritis-induced emesis in dogs. J Vet Pharmacol Ther. 2017;40(6):599-603. doi:10.2754/avb200574010111 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.984 (2026-08-01).. Ondansetron Injectable is used in dogs for Acute vomiting (hospitalized). Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ondansetron Injectable in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zofran Injectable
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.1–0.5 mg/kg | q8-12h IV | As needed | Acute vomiting (hospitalized) | Strong | Topal A, Kaya M, Gul N. Ondansetron and granisetron in the prophylaxis of nausea and emesis induced by cisplatin in dogs. Acta Vet Brno. 2005;74(1):111-116. / 1. Yalcin E, Keser GO. Comparative efficacy of metoclopramide, ondansetron and maropitant in preventing parvoviral enteritis-induced emesis in dogs. J Vet Pharmacol Ther. 2017;40(6):599-603. doi:10.2754/avb200574010111 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.984 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
5-HT3 serotonin receptor antagonist. Injectable form for acute nausea/vomiting in hospitalized patients unable to take oral medication.
IV route for acute vomiting/nausea. Often combined with maropitant for refractory vomiting. Constipation possible. QT prolongation at high doses.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ondansetron Injectable dose range in dogs, with cited source references: IV 0.1–0.5 mg/kg q8-12h IV. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ondansetron Injectable in dogs: IV.
Cited course lengths for Ondansetron Injectable in dogs include: As needed. Duration depends on the indication — match it to the specific dose rule in the table above.
Ondansetron Injectable is indicated in dogs for: Acute vomiting (hospitalized).
These are general warnings for Ondansetron Injectable across species; consult the dog dosing table above for species-specific guidance. IV route for acute vomiting/nausea. Often combined with maropitant for refractory vomiting. Constipation possible. QT prolongation at high doses.
Why a species-specific page? Ondansetron Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.