Ondansetron Injectable for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Ondansetron Injectable is used in dog for Acute vomiting (hospitalized). Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ondansetron Injectable in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Zofran Injectable
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.1–0.5 mg/kg | q8-12h IV | As needed | Acute vomiting (hospitalized) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
5-HT3 serotonin receptor antagonist. Injectable form for acute nausea/vomiting in hospitalized patients unable to take oral medication.
Side effects & warnings
IV route for acute vomiting/nausea. Often combined with maropitant for refractory vomiting. Constipation possible. QT prolongation at high doses.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Gastrointestinal drugs with dog dosing
Ondansetron Injectable dosing in other species
Why a species-specific page? Ondansetron Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.