Cat · Felis catus · typical adult weight 2.50–7.00 kg
Ondansetron Injectable is dosed at 0.1–0.5 mg/kg IV q8-12h IV in cats, per Quimby JM, Lake RC, Hansen RJ, Lunghofer PJ, Gustafson DL. Oral, subcutaneous, and intravenous pharmacokinetics of ondansetron in healthy cats. J Vet Pharmacol Ther. 2014;37(4):348-353. doi:10.1111/jvp.12094 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.984 (2026-08-01). — Plumb's 10th ed (held) printed p.956, Ondansetron monograph spanning p.956-957; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Ondansetron Injectable is used in cats for Acute vomiting. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Ondansetron Injectable in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zofran Injectable
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.1–0.5 mg/kg | q8-12h IV | As needed | Acute vomiting | Moderate | Quimby JM, Lake RC, Hansen RJ, Lunghofer PJ, Gustafson DL. Oral, subcutaneous, and intravenous pharmacokinetics of ondansetron in healthy cats. J Vet Pharmacol Ther. 2014;37(4):348-353. doi:10.1111/jvp.12094 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.984 (2026-08-01). — Plumb's 10th ed (held) printed p.956, Ondansetron monograph spanning p.956-957; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.5 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.309 | 0.5 mg/kg i.v. loading dose followed by 0.5 mg/kg/h infusion for 6 hours or 0.5-1 mg/kg p.o. q12-24 |
| 0.5–1 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.309 | oading dose followed by 0.5 mg/kg/h infusion for 6 hours or 0.5-1 mg/kg p.o. q12-24h. |
| 0.5 | SC | Papich Saunders Handbook of Veterinary Drugs, 4th edp.609 | • Similar doses as dogs have been administered, or 0.5 mg/kg q12h SQ, IV, or PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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5-HT3 serotonin receptor antagonist. Injectable form for acute nausea/vomiting in hospitalized patients unable to take oral medication.
IV route for acute vomiting/nausea. Often combined with maropitant for refractory vomiting. Constipation possible. QT prolongation at high doses.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ondansetron Injectable dose range in cats, with cited source references: IV 0.1–0.5 mg/kg q8-12h IV. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ondansetron Injectable in cats: IV.
Cited course lengths for Ondansetron Injectable in cats include: As needed. Duration depends on the indication — match it to the specific dose rule in the table above.
Ondansetron Injectable is indicated in cats for: Acute vomiting.
These are general warnings for Ondansetron Injectable across species; consult the cat dosing table above for species-specific guidance. IV route for acute vomiting/nausea. Often combined with maropitant for refractory vomiting. Constipation possible. QT prolongation at high doses.
Why a species-specific page? Ondansetron Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.