Fipronil for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Fipronil is used in dog for Flea and tick control. Routes documented in dog: TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Fipronil in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Frontline
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | 6.7 mg/kg | q30d | Monthly application | Flea and tick control | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Blocks GABA-gated chloride channels in invertebrate nervous system, causing hyperexcitation and death of fleas and ticks.
Side effects & warnings
TOXIC to rabbits. External use only. May cause transient skin irritation. Seizures reported in rabbits — do NOT use in rabbits. Safe in dogs and cats.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antiparasitic drugs with dog dosing
Fipronil dosing in other species
Why a species-specific page? Fipronil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.