Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Fipronil is dosed at 6.7 mg/kg TOPICAL q30d in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1480 (2026-08-01).. Fipronil is used in dogs for Flea and tick control. Routes documented in dogs: TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Fipronil in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Frontline
Contraindicated in Rabbit
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | 6.7 mg/kg | q30d | Monthly application | Flea and tick control | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1480 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Blocks GABA-gated chloride channels in invertebrate nervous system, causing hyperexcitation and death of fleas and ticks.
TOXIC to rabbits. External use only. May cause transient skin irritation. Seizures reported in rabbits — do NOT use in rabbits. Safe in dogs and cats.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Fipronil dose range in dogs, with cited source references: TOPICAL 6.7 mg/kg q30d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Fipronil in dogs: TOPICAL.
Cited course lengths for Fipronil in dogs include: Monthly application. Duration depends on the indication — match it to the specific dose rule in the table above.
Fipronil is indicated in dogs for: Flea and tick control.
These are general warnings for Fipronil across species; consult the dog dosing table above for species-specific guidance. TOXIC to rabbits. External use only. May cause transient skin irritation. Seizures reported in rabbits — do NOT use in rabbits. Safe in dogs and cats.
Why a species-specific page? Fipronil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.