Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Fipronil is dosed at 6.7 applicator per weight band (NOT mg/kg) TOPICAL q30d in dogs, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1480 (2026-08-01). — Plumb's 10th ed (held) printed p.1453, Fipronil/Fipronil Combinations, Topical monograph spanning p.1453-1455; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 BASIS CORRECTED 2026-08-13: served as exact mg/kg, which the calculator multiplies by body weight to produce a milligram figure for a product that is a fixed-volume topical pipette. Plumb's 10th ed, Fipronil Topical monograph, corpus p.1481, Dosage Forms: "Fipronil 9.7% (spot-on solution) ... single-dose applicators 0.5 mL in packages of 3 and 6", labelled "for use on cats and kittens 8 weeks of age or older and over 0.7 kg" - i.e. selected by WEIGHT BAND, not calculated per kilogram. The served 6.7 mg/kg is a derived figure, not a printed dose. Read from the page 2026-08-13.. Fipronil is used in dogs for Flea and tick control. Routes documented in dogs: TOPICAL. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Fipronil in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Frontline
Contraindicated in Rabbit
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL | 6.7 applicator per weight band (NOT mg/kg) | q30d | Monthly application | Flea and tick control | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1480 (2026-08-01). — Plumb's 10th ed (held) printed p.1453, Fipronil/Fipronil Combinations, Topical monograph spanning p.1453-1455; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 BASIS CORRECTED 2026-08-13: served as exact mg/kg, which the calculator multiplies by body weight to produce a milligram figure for a product that is a fixed-volume topical pipette. Plumb's 10th ed, Fipronil Topical monograph, corpus p.1481, Dosage Forms: "Fipronil 9.7% (spot-on solution) ... single-dose applicators 0.5 mL in packages of 3 and 6", labelled "for use on cats and kittens 8 weeks of age or older and over 0.7 kg" - i.e. selected by WEIGHT BAND, not calculated per kilogram. The served 6.7 mg/kg is a derived figure, not a printed dose. Read from the page 2026-08-13. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (ml/kg) | Route | Source | As printed |
|---|---|---|---|
| 3–6 | — | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.180 | spray 3-6 ml/kg (6-12 pumps/kg 100 ml application, 2-4 pumps/kg 250 ml or 500 ml application) |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Blocks GABA-gated chloride channels in invertebrate nervous system, causing hyperexcitation and death of fleas and ticks.
TOXIC to rabbits. External use only. May cause transient skin irritation. Seizures reported in rabbits — do NOT use in rabbits. Safe in dogs and cats.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Fipronil dose range in dogs, with cited source references: TOPICAL 6.7 applicator per weight band (NOT mg/kg) q30d. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Fipronil in dogs: TOPICAL.
Cited course lengths for Fipronil in dogs include: Monthly application. Duration depends on the indication — match it to the specific dose rule in the table above.
Fipronil is indicated in dogs for: Flea and tick control.
These are general warnings for Fipronil across species; consult the dog dosing table above for species-specific guidance. TOXIC to rabbits. External use only. May cause transient skin irritation. Seizures reported in rabbits — do NOT use in rabbits. Safe in dogs and cats.
Why a species-specific page? Fipronil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.