Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Milbemycin Oxime Injectable is used in dogs for Heartworm prevention (6 or 12 months). Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Milbemycin Oxime Injectable in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | Administered by veterinarian only | One injection q6 or q12 months | Single injection | Heartworm prevention (6 or 12 months) | Strong | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.885, Milbemycin Oxime monograph spanning p.885-886; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.560 | • Heartworm prevention and control of endoparasites: 0.5 mg/kg q30days PO. |
| 2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.560 | • Demodicosis: 2 mg/kg q24h PO for 60-120 days or 1 mg/kg daily until a clini- |
| 1 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.560 | • Demodicosis: 2 mg/kg q24h PO for 60-120 days or 1 mg/kg daily until a clini- |
| 3 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.560 | cal cure is observed, followed by 3 mg/kg once per week until a parasitological |
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Sustained-release moxidectin (ProHeart) microspheres providing 6 or 12 months of heartworm prevention. Potentiates glutamate-gated chloride channels.
Single SC injection for 6-12 months heartworm prevention. Anaphylaxis risk (monitor 30 min post-injection). Not for dogs <12 months old. Must be administered by veterinarian.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Milbemycin Oxime Injectable dose range in dogs, with cited source references: SC Administered by veterinarian only One injection q6 or q12 months. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Milbemycin Oxime Injectable in dogs: SC.
Cited course lengths for Milbemycin Oxime Injectable in dogs include: Single injection. Duration depends on the indication — match it to the specific dose rule in the table above.
Milbemycin Oxime Injectable is indicated in dogs for: Heartworm prevention (6 or 12 months).
These are general warnings for Milbemycin Oxime Injectable across species; consult the dog dosing table above for species-specific guidance. Single SC injection for 6-12 months heartworm prevention. Anaphylaxis risk (monitor 30 min post-injection). Not for dogs <12 months old. Must be administered by veterinarian.
Why a species-specific page? Milbemycin Oxime Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.