Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tripelennamine is used in dog for Allergic reactions, urticaria, pruritus. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Tripelennamine in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Pelamine, Re-Covr
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q8-12h | As needed for allergic signs | Allergic reactions, urticaria, pruritus | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
First-generation H1-antihistamine that competitively blocks histamine at H1 receptors, reducing histamine-mediated vasodilation, increased vascular permeability, and pruritus.
Sedation is common. Anticholinergic side effects (dry mouth, urinary retention). Used primarily in horses and cattle. Largely replaced by newer antihistamines in small animals.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Tripelennamine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.