Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Thiostrepton is used in dogs for Bacterial skin infections, otitis externa (in combination). Routes documented in dogs: Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Thiostrepton in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Panolog
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | Available only in combination products (Panolog: nystatin, neomycin, thiostrepton, triamcinolone) | q12-24h | 7-14 days | Bacterial skin infections, otitis externa (in combination) | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1466 (2026-08-01). |
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Thiopeptide antibiotic that binds to the 23S rRNA of the 50S ribosomal subunit, inhibiting bacterial protein synthesis. Active primarily against gram-positive bacteria.
Available only in combination products (with nystatin, neomycin, triamcinolone). Topical use only. Hypersensitivity reactions possible. Do not use near eyes.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Thiostrepton dose range in dogs, with cited source references: Topical Available only in combination products (Panolog: nystatin, neomycin, thiostrepton, triamcinolone) q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Thiostrepton in dogs: Topical.
Cited course lengths for Thiostrepton in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Thiostrepton is indicated in dogs for: Bacterial skin infections, otitis externa (in combination).
These are general warnings for Thiostrepton across species; consult the dog dosing table above for species-specific guidance. Available only in combination products (with nystatin, neomycin, triamcinolone). Topical use only. Hypersensitivity reactions possible. Do not use near eyes.
Why a species-specific page? Thiostrepton pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.