Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tacrolimus Topical is used in dogs for Perianal fistulas, localized atopic dermatitis, Discoid lupus erythematosus. Routes documented in dogs: Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Tacrolimus Topical in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Protopic
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | 0.1% ointment | q12h | 8-16 weeks for fistulas | Perianal fistulas, localized atopic dermatitis | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1492 (2026-08-01). |
| Topical | 0.1% ointment applied to affected areas | q12h | Long-term | Discoid lupus erythematosus |
| Moderate |
| Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1492 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits calcineurin-mediated T-cell activation. Reduces local immune response and inflammation without steroid side effects (no skin atrophy).
Used for localized atopic dermatitis, perianal fistulas (anal furunculosis), and discoid lupus. Initial burning sensation. No skin atrophy. More expensive than steroids.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tacrolimus Topical dose ranges in dogs, with cited source references: Topical 0.1% ointment q12h; Topical 0.1% ointment applied to affected areas q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tacrolimus Topical in dogs: Topical.
Cited course lengths for Tacrolimus Topical in dogs include: 8-16 weeks for fistulas; Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Tacrolimus Topical is indicated in dogs for: Perianal fistulas, localized atopic dermatitis, Discoid lupus erythematosus.
These are general warnings for Tacrolimus Topical across species; consult the dog dosing table above for species-specific guidance. Used for localized atopic dermatitis, perianal fistulas (anal furunculosis), and discoid lupus. Initial burning sensation. No skin atrophy. More expensive than steroids.
Why a species-specific page? Tacrolimus Topical pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.