Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Tacrolimus Topical is used in dogs for Perianal fistulas, localized atopic dermatitis. Routes documented in dogs: Topical. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Tacrolimus Topical in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Protopic
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Topical | See the cited source for the printed regimen | q12h | 8-16 weeks for fistulas | Perianal fistulas, localized atopic dermatitis | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1492 (2026-08-01). — Plumb's 10th ed (held) printed p.1402, Tacrolimus Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (%) | Route | Source | As printed |
|---|---|---|---|
| 0.1 | TOPICAL | Papich Saunders Handbook of Veterinary Drugs, 4th edp.786 | • Apply topical ointment (0.1%) to localized lesions on affected areas of skin. It has |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Inhibits calcineurin-mediated T-cell activation. Reduces local immune response and inflammation without steroid side effects (no skin atrophy).
Used for localized atopic dermatitis, perianal fistulas (anal furunculosis), and discoid lupus. Initial burning sensation. No skin atrophy. More expensive than steroids.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Tacrolimus Topical dose range in dogs, with cited source references: Topical See the cited source for the printed regimen q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Tacrolimus Topical in dogs: Topical.
Cited course lengths for Tacrolimus Topical in dogs include: 8-16 weeks for fistulas. Duration depends on the indication — match it to the specific dose rule in the table above.
Tacrolimus Topical is indicated in dogs for: Perianal fistulas, localized atopic dermatitis.
These are general warnings for Tacrolimus Topical across species; consult the dog dosing table above for species-specific guidance. Used for localized atopic dermatitis, perianal fistulas (anal furunculosis), and discoid lupus. Initial burning sensation. No skin atrophy. More expensive than steroids.
Why a species-specific page? Tacrolimus Topical pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.