Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Phenylephrine Injectable is dosed at 0.001–0.003 mg/kg/min CRI IV CRI titrated to effect in dogs, per Ko J. Anesthesia monitoring techniques and management. Presented at: Proceedings: ACVC; 2009. PMID: 42484292 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1043 (2026-08-01).. Phenylephrine Injectable is used in dogs for Vasodilatory shock/Severe hypotension. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Phenylephrine Injectable in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Neo-Synephrine Injectable
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.001–0.003 mg/kg/min CRI | CRI titrated to effect | CRI until hemodynamics stabilize; taper gradually | Vasodilatory shock/Severe hypotension | Moderate | Ko J. Anesthesia monitoring techniques and management. Presented at: Proceedings: ACVC; 2009. PMID: 42484292 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1043 (2026-08-01). |
One of the cited rules is a continuous-rate-infusion regimen: IV 0.001–0.003 mg/kg/min CRI CRI titrated to effect. CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selective alpha-1 adrenergic agonist causing peripheral vasoconstriction, increasing systemic vascular resistance and blood pressure without significant cardiac stimulation.
Reflex bradycardia common. Extravasation causes tissue necrosis — use central line when possible. Contraindicated in severe hypertension. Titrate to effect.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Phenylephrine Injectable dose range in dogs, with cited source references: IV 0.001–0.003 mg/kg/min CRI CRI titrated to effect. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Phenylephrine Injectable in dogs: IV.
Cited course lengths for Phenylephrine Injectable in dogs include: CRI until hemodynamics stabilize; taper gradually. Duration depends on the indication — match it to the specific dose rule in the table above.
Phenylephrine Injectable is indicated in dogs for: Vasodilatory shock/Severe hypotension.
These are general warnings for Phenylephrine Injectable across species; consult the dog dosing table above for species-specific guidance. Reflex bradycardia common. Extravasation causes tissue necrosis — use central line when possible. Contraindicated in severe hypertension. Titrate to effect.
Why a species-specific page? Phenylephrine Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.