Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Phenylephrine Injectable is dosed at 0.001–0.003 mg/kg/min CRI IV CRI titrated to effect in dogs, per Ko J. Anesthesia monitoring techniques and management. Presented at: Proceedings: ACVC; 2009.. Phenylephrine Injectable is used in dogs for Vasodilatory shock/Severe hypotension. Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Phenylephrine Injectable in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Neo-Synephrine Injectable
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 0.001–0.003 mg/kg/min CRI | CRI titrated to effect | CRI until hemodynamics stabilize; taper gradually | Vasodilatory shock/Severe hypotension | Moderate | Ko J. Anesthesia monitoring techniques and management. Presented at: Proceedings: ACVC; 2009. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mcg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.660 | • 10 mcg/kg (0.01 mg/kg) q15min IV as needed or 0.1 mg/kg q15min IM or SQ. |
| 3 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.660 | • CRI: 10 mcg/kg (0.01 mg/kg) IV, followed by 3 mcg/kg/min IV. |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.01 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.336 | correct blood volume then infuse 0.01 mg/kg very slowly i.v. q15min. Continuously monitor blood pressure if possible. |
| 0.01 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.660 | • 10 mcg/kg (0.01 mg/kg) q15min IV as needed or 0.1 mg/kg q15min IM or SQ. |
| 0.1 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.660 | • 10 mcg/kg (0.01 mg/kg) q15min IV as needed or 0.1 mg/kg q15min IM or SQ. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
One of the cited rules is a continuous-rate-infusion regimen: IV 0.001–0.003 mg/kg/min CRI CRI titrated to effect. CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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Selective alpha-1 adrenergic agonist causing peripheral vasoconstriction, increasing systemic vascular resistance and blood pressure without significant cardiac stimulation.
Reflex bradycardia common. Extravasation causes tissue necrosis — use central line when possible. Contraindicated in severe hypertension. Titrate to effect.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Phenylephrine Injectable dose range in dogs, with cited source references: IV 0.001–0.003 mg/kg/min CRI CRI titrated to effect. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Phenylephrine Injectable in dogs: IV.
Cited course lengths for Phenylephrine Injectable in dogs include: CRI until hemodynamics stabilize; taper gradually. Duration depends on the indication — match it to the specific dose rule in the table above.
Phenylephrine Injectable is indicated in dogs for: Vasodilatory shock/Severe hypotension.
These are general warnings for Phenylephrine Injectable across species; consult the dog dosing table above for species-specific guidance. Reflex bradycardia common. Extravasation causes tissue necrosis — use central line when possible. Contraindicated in severe hypertension. Titrate to effect.
Why a species-specific page? Phenylephrine Injectable pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.