Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Dinoprost is dosed at 0.025–0.25 mg/kg SC q12-24h in dogs, per Smith FO. Pyometra. In: Bonagura JD, Twedt DC, eds. Kirk's Current Veterinary Therapy XV. Saunders Elsevier; 2014:967-969. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.434 (2026-08-01).. Dinoprost is used in dogs for Open pyometra. Routes documented in dogs: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Dinoprost in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Lutalyse
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| SC | 0.025–0.25 mg/kg | q12-24h | 3-7 days | Open pyometra | Moderate | Smith FO. Pyometra. In: Bonagura JD, Twedt DC, eds. Kirk's Current Veterinary Therapy XV. Saunders Elsevier; 2014:967-969. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.434 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Natural prostaglandin F2α causing luteolysis, myometrial contraction, and cervical dilation. Shorter duration of action than synthetic analogs.
Causes salivation, vomiting, diarrhea, panting in dogs/cats. Handle with extreme caution (abortifacient). Used for pyometra and pregnancy termination.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Dinoprost dose range in dogs, with cited source references: SC 0.025–0.25 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Dinoprost in dogs: SC.
Cited course lengths for Dinoprost in dogs include: 3-7 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Dinoprost is indicated in dogs for: Open pyometra.
These are general warnings for Dinoprost across species; consult the dog dosing table above for species-specific guidance. Causes salivation, vomiting, diarrhea, panting in dogs/cats. Handle with extreme caution (abortifacient). Used for pyometra and pregnancy termination.
Why a species-specific page? Dinoprost pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.