Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Sulfadiazine is dosed at 15–25 mg/kg PO q12h in dogs, per Weese JS, Blondeau J, Boothe D, et al. International Society for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats. Vet J. 2019;247:8-25. doi:10.1016/j.tvjl.2019.02.008 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1222 (2026-08-01).. Sulfadiazine is used in dogs for Susceptible infections (with trimethoprim). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Sulfadiazine in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 15–25 mg/kg | q12h | 7-14 days | Susceptible infections (with trimethoprim) | Strong | Weese JS, Blondeau J, Boothe D, et al. International Society for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats. Vet J. 2019;247:8-25. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1222 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Competitive inhibitor of dihydropteroate synthase in folate synthesis pathway. Bacteriostatic alone; bactericidal when combined with trimethoprim.
Ensure adequate hydration to prevent crystalluria. KCS risk in dogs with prolonged use. Avoid in hepatic insufficiency. Folate supplementation may be needed.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Sulfadiazine dose range in dogs, with cited source references: PO 15–25 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Sulfadiazine in dogs: PO.
Cited course lengths for Sulfadiazine in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Sulfadiazine is indicated in dogs for: Susceptible infections (with trimethoprim).
These are general warnings for Sulfadiazine across species; consult the dog dosing table above for species-specific guidance. Ensure adequate hydration to prevent crystalluria. KCS risk in dogs with prolonged use. Avoid in hepatic insufficiency. Folate supplementation may be needed.
Why a species-specific page? Sulfadiazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.