Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Levamisole is dosed at 2–5 mg/kg PO q48h in dogs, per Johnson KC, Mackin A. Canine immune-mediated polyarthritis: part 2: diagnosis and treatment. J Am Anim Hosp Assoc. 2012;48(2):71-82. PMID: 22267168 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.771 (2026-08-01).. Levamisole is used in dogs for Immunomodulation. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Levamisole in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Levasole, Tramisol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–5 mg/kg | q48h | Variable | Immunomodulation | Weak | Johnson KC, Mackin A. Canine immune-mediated polyarthritis: part 2: diagnosis and treatment. J Am Anim Hosp Assoc. 2012;48(2):71-82. PMID: 22267168 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.771 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Nicotinic acetylcholine receptor agonist causing sustained muscle contraction and paralysis in nematodes. Also has immunostimulant properties.
Narrow safety margin — toxicity causes cholinergic signs (salivation, tremors, dyspnea). TOXIC to dogs at high doses. Immunomodulatory use at low doses.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Levamisole dose range in dogs, with cited source references: PO 2–5 mg/kg q48h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Levamisole in dogs: PO.
Cited course lengths for Levamisole in dogs include: Variable. Duration depends on the indication — match it to the specific dose rule in the table above.
Levamisole is indicated in dogs for: Immunomodulation.
These are general warnings for Levamisole across species; consult the dog dosing table above for species-specific guidance. Narrow safety margin — toxicity causes cholinergic signs (salivation, tremors, dyspnea). TOXIC to dogs at high doses. Immunomodulatory use at low doses.
Why a species-specific page? Levamisole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.