Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Unoprostone Ophthalmic is used in dogs for Glaucoma (milder prostaglandin analogue). Routes documented in dogs: Ophthalmic. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Unoprostone Ophthalmic in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Rescula
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Ophthalmic | Less potent IOP reduction than latanoprost but may cause less uveitis | 1 drop affected eye q12h | Chronic use | Glaucoma (milder prostaglandin analogue) | Weak | Gelatt, K.N. & MacKay, E.O. (2001a); Ofri, R., et al. (2000) - cited in Gelatt, Veterinary Ophthalmology 6th ed., 8.5 Clinical Pharmacology and Therapeutics — Verified against Veterinary Ophthalmology (Gelatt), 6th Ed, p.486 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Docosanoid prostaglandin analogue that increases uveoscleral and trabecular outflow. Less potent than latanoprost but may cause less inflammation in uveitis-prone eyes.
Milder IOP reduction than other prostaglandin analogues. May be better tolerated in eyes with prior uveitis. BID dosing (vs QD for other PGAs). Limited veterinary data.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Unoprostone Ophthalmic dose range in dogs, with cited source references: Ophthalmic Less potent IOP reduction than latanoprost but may cause less uveitis 1 drop affected eye q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Unoprostone Ophthalmic in dogs: Ophthalmic.
Cited course lengths for Unoprostone Ophthalmic in dogs include: Chronic use. Duration depends on the indication — match it to the specific dose rule in the table above.
Unoprostone Ophthalmic is indicated in dogs for: Glaucoma (milder prostaglandin analogue).
These are general warnings for Unoprostone Ophthalmic across species; consult the dog dosing table above for species-specific guidance. Milder IOP reduction than other prostaglandin analogues. May be better tolerated in eyes with prior uveitis. BID dosing (vs QD for other PGAs). Limited veterinary data.
Why a species-specific page? Unoprostone Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.