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Unoprostone Ophthalmic

Rescula

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Ophthalmic

Routes

Ophthalmic

Indications

GlaucomaGlaucoma (milder prostaglandin analogue)

Mechanism of Action

Docosanoid prostaglandin analogue that increases uveoscleral and trabecular outflow. Less potent than latanoprost but may cause less inflammation in uveitis-prone eyes.

Side effects & warnings

Milder IOP reduction than other prostaglandin analogues. May be better tolerated in eyes with prior uveitis. BID dosing (vs QD for other PGAs). Limited veterinary data.

Species with Unoprostone Ophthalmic dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Weak×1Anecdotal×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Gelatt KN, Veterinary Ophthalmology, 6th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)Ophthalmic0 mg/kg1 drop affected eye q12hWeakGelatt KN, Veterinary Ophthalmology, 6th Ed
Cat (Domestic)Ophthalmic0 mg/kg1 drop affected eye q12hAnecdotalGelatt KN, Veterinary Ophthalmology, 6th Ed

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