Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Omeprazole Paste is dosed at 1–2 mg/kg PO q24h in dogs, per Bersenas AM, Mathews KA, Allen DG, Conlon PD. Effects of ranitidine, famotidine, pantoprazole, and omeprazole on intragastric pH in dogs. Am J Vet Res. 2005;66(3):425-431. doi:10.2460/ajvr.2005.66.425 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.981 (2026-08-01). — Plumb's 10th ed (held) printed p.953, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Omeprazole Paste is used in dogs for Gastric ulceration (equine formulation used off-label). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Omeprazole Paste in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: GastroGard, UlcerGard
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q24h | 2-8 weeks | Gastric ulceration (equine formulation used off-label) | Moderate | Bersenas AM, Mathews KA, Allen DG, Conlon PD. Effects of ranitidine, famotidine, pantoprazole, and omeprazole on intragastric pH in dogs. Am J Vet Res. 2005;66(3):425-431. doi:10.2460/ajvr.2005.66.425 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.981 (2026-08-01). — Plumb's 10th ed (held) printed p.953, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.5–1.5 | IV | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.308 | 0.5-1.5 mg/kg i.v., p.o. q12-24h for a maximum of 8 weeks |
| 1–2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.607 | • 20 mg per dog q24h PO or 1-2 mg/kg • 1 mg/kg q24h PO. |
| 1 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.607 | • 20 mg per dog q24h PO or 1-2 mg/kg • 1 mg/kg q24h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Same as oral omeprazole. Paste formulation designed for equine administration.
FDA-approved for horses (gastric ulcers). GastroGard is treatment dose, UlcerGard is prevention dose. Give on empty stomach. Buffered formulation to protect from stomach acid.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Omeprazole Paste dose range in dogs, with cited source references: PO 1–2 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Omeprazole Paste in dogs: PO.
Cited course lengths for Omeprazole Paste in dogs include: 2-8 weeks. Duration depends on the indication — match it to the specific dose rule in the table above.
Omeprazole Paste is indicated in dogs for: Gastric ulceration (equine formulation used off-label).
These are general warnings for Omeprazole Paste across species; consult the dog dosing table above for species-specific guidance. FDA-approved for horses (gastric ulcers). GastroGard is treatment dose, UlcerGard is prevention dose. Give on empty stomach. Buffered formulation to protect from stomach acid.
Why a species-specific page? Omeprazole Paste pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.