Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Methylprednisolone is dosed at 0.5–2 mg/kg PO q12-24h, then taper in dogs, per BSAVA Small Animal Formulary 10th Ed, Part A - Canine and Feline, p.260 (corpus PDF p.276), Methylprednisolone, DOSES, Dogs — 0.2-0.5 mg/kg p.o. q12h (inflammation) and 1-3 mg/kg p.o. q12h (immunosuppression); mid-range corroborated by Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) p.865 0.4-0.8 mg/kg PO q12-24h — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Methylprednisolone is used in dogs for Anti-inflammatory / immunosuppressive. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Methylprednisolone in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Medrol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q12-24h, then taper | Short to medium-term; taper over 2-4 weeks | Anti-inflammatory / immunosuppressive | Weak | BSAVA Small Animal Formulary 10th Ed, Part A - Canine and Feline, p.260 (corpus PDF p.276), Methylprednisolone, DOSES, Dogs — 0.2-0.5 mg/kg p.o. q12h (inflammation) and 1-3 mg/kg p.o. q12h (immunosuppression); mid-range corroborated by Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) p.865 0.4-0.8 mg/kg PO q12-24h — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705; Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/animal) | Route | Source | As printed |
|---|---|---|---|
| 20–40 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone acetate: 1 mg/kg (or 20-40 mg/dog) IM q1-3wk. |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.2–0.5 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 | ylprednisolone acetate depot injection) q1-3wk or 0.2-0.5 mg/kg p.o. q12h. • Hypoadrenocorticism (acute crisis): 1 mg/kg i.v. once daily until |
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Intermediate-acting synthetic glucocorticoid that suppresses inflammation and immune responses via glucocorticoid receptor-mediated gene transcription changes.
PU/PD, polyphagia, hepatomegaly with chronic use. Taper gradually. Less mineralocorticoid effect than cortisone or hydrocortisone.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Methylprednisolone dose range in dogs, with cited source references: PO 0.5–2 mg/kg q12-24h, then taper. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Methylprednisolone in dogs: PO.
Cited course lengths for Methylprednisolone in dogs include: Short to medium-term; taper over 2-4 weeks. Duration depends on the indication — match it to the specific dose rule in the table above.
Methylprednisolone is indicated in dogs for: Anti-inflammatory / immunosuppressive.
These are general warnings for Methylprednisolone across species; consult the dog dosing table above for species-specific guidance. PU/PD, polyphagia, hepatomegaly with chronic use. Taper gradually. Less mineralocorticoid effect than cortisone or hydrocortisone.
Why a species-specific page? Methylprednisolone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 1 |
| IV |
| BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 |
| .5 mg/kg p.o. q12h. • Hypoadrenocorticism (acute crisis): 1 mg/kg i.v. once daily until oral supplementation started. |
| 1–3 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 | 1-3 mg/kg p.o. q12h reducing to 1-2 mg/ kg p.o. q48h |
| 1.1 | IM | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.276 | initially 1.1 mg/kg i.m. (methylprednisolone acetate depot injection) q1-3wk or 0.2-0.5 mg/kg p.o. |
| 1 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone acetate: 1 mg/kg (or 20-40 mg/dog) IM q1-3wk. |
| 30 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone sodium succinate (for emergency use): 30 mg/kg IV and |
| 15 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | repeat at 15 mg/kg in 2-6 hours IV. Replacement or anti-inflammatory therapy: |
| 0.25–0.5 | — | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | use 0.25-0.5 mg/kg/day. |
| 0.22–0.44 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.547 | • Methylprednisolone: 0.22-0.44 mg/kg q12-24h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.