Cat · Felis catus · typical adult weight 2.50–7.00 kg
Methylprednisolone is dosed at 0.5–2 mg/kg PO q12-24h, then taper in cats, per Yu A. What's New in Atopic Dermatitis in Cats? Proceedings 66th Convention of the Canadian Veterinary Medical Association. Published online 2014.; Ganz EC, Griffin CE, Keys DA, Flatgard TA. Evaluation of methylprednisolone and triamcinolone for the induction and maintenance treatment of pruritus in allergic cats: a double-blinded, randomized, prospective study. Vet Dermatol. 2012;23(5):387-e72. doi:10.1111/j.1365-3164.2012.01058.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.893 (2026-08-01).. Methylprednisolone is used in cats for Anti-inflammatory / immune-mediated disease. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Methylprednisolone in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Medrol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q12-24h, then taper | Short to medium-term; taper to lowest effective dose | Anti-inflammatory / immune-mediated disease | Strong | Yu A. What's New in Atopic Dermatitis in Cats? Proceedings 66th Convention of the Canadian Veterinary Medical Association. Published online 2014.; Ganz EC, Griffin CE, Keys DA, Flatgard TA. Evaluation of methylprednisolone and triamcinolone for the induction and maintenance treatment of pruritus in allergic cats: a double-blinded, randomized, prospective study. Vet Dermatol. 2012;23(5):387-e72. doi:10.1111/j.1365-3164.2012.01058.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.893 (2026-08-01). |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Intermediate-acting synthetic glucocorticoid that suppresses inflammation and immune responses via glucocorticoid receptor-mediated gene transcription changes.
PU/PD, polyphagia, hepatomegaly with chronic use. Taper gradually. Less mineralocorticoid effect than cortisone or hydrocortisone.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Methylprednisolone dose range in cats, with cited source references: PO 0.5–2 mg/kg q12-24h, then taper. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Methylprednisolone in cats: PO.
Cited course lengths for Methylprednisolone in cats include: Short to medium-term; taper to lowest effective dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Methylprednisolone is indicated in cats for: Anti-inflammatory / immune-mediated disease.
These are general warnings for Methylprednisolone across species; consult the cat dosing table above for species-specific guidance. PU/PD, polyphagia, hepatomegaly with chronic use. Taper gradually. Less mineralocorticoid effect than cortisone or hydrocortisone.
Why a species-specific page? Methylprednisolone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.