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Darbepoetin for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Darbepoetin is used in cat for Anemia of chronic kidney disease. Routes documented in cat: SC. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Darbepoetin in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Aranesp

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
SC0.001 mcg/kgq1-2 weeksLong-term; titrate to PCV 25-35%Anemia of chronic kidney diseaseModeratePlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Hyperglycosylated analog of erythropoietin with longer half-life. Stimulates red blood cell production from erythroid progenitor cells.

Side effects & warnings

Monitor PCV/HCT closely. Risk of pure red cell aplasia from antibody formation. Supplement iron. Avoid if PCV rising too rapidly.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Endocrine drugs with cat dosing

Darbepoetin dosing in other species

Why a species-specific page? Darbepoetin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.